Table of Contents

1  The Ethical Debate on Evidence‑based Medicine

     Introduction to the Volume .................................................................................................... 1

     Ruud ter Meulen ‑ Nikola Biller‑Andorno ‑ Christian Lenk ‑ Reidar Lie

2 Regulating Health Care. The Development of Guidelines

     in Medical Practice and Health Policy ................................................................................ 9

     Christine Sepers ‑ Ruud ter Meulen

3 Evidence‑based Medicine and Power Shifts in Health Care Systems ...................... 17

     Rein Vos ‑ Rob Houtepen ‑ Klasien Horstman

4 Beyond Legitimate Science: The Case for Policy‑Related Science ........................... 25

     Mariachiara Tallacchini

5 Teaching Evidence‑based Medicine .................................................................................. 35

     Franz Porzsolt ‑ Heike Leonhardt‑Huober

6 Evidence‑based Medicine and Clinical Guidelines in Cardiology.

     Promoting Science, Practice, or Bureaucracy? ............................................................. 45

     Frank Praetorius

7 Are Particular Patients Disadvantaged by EBM?

     Focus on Frail Elderly Patients ............................................................................................ 61

     Fabrizio Fabris ‑ Carla Scarafiotti ‑ Barbara Maero

8 Evidence‑based Medicine in Mental Health: Towards Better and

     Fairer Treatment? .................................................................................................................. 65

     Andreas Reis ‑ Christian Lenk ‑ Cristiane Reis‑Streussnig ‑ Nikola Biller‑Andorno

9 Current Epistemological Problems in Evidence‑based Medicine .............................. 77

     Richard E. Ashcroft

10 Coordinating the Norms and Values of Medical Research, Medical

     Practice and Patient Worlds. The Ethics of Evidence‑based Medicine in

     'Boundary Fields of Medicine’ .............................................................................................. 87

     Rein Vos ‑ Dick Willems ‑ Rob Houtepen

11 Research Ethics and Evidence‑based Medicine ........................................................... 97

     Reidar K. Lie

12 Clinical Evaluative Research: Which Patients Benefit, How and When?

     A Contribution to a European Discussion ........................................................................ 105

     Heiner Raspe

13 Defining a Proper Background for Discussing Evidence‑based

     Medicine .................................................................................................................................. 117

     Alessandro Liberati ‑ Paolo Vineis

14 Evidence‑based Medicine and Equity: The Exclusion of

     Disadvantaged Groups ......................................................................................................... 129

     Wendy A. Rogers

15 The Role of Formal Outcome Evaluations in Health Policy Making:

     A Normative Perspective ..................................................................................................... 139

     Ole F. Norheirn

16 The Usefulness of Formal Outcome Evaluations in Health Policy

     Making: Looking for the Baby in the Bathwater ............................................................. 151

     Erik Nord

17 Evidence‑based Medicine and Managed Care .............................................................. 163

     Marion Danis

18 Recommendations from the Evibase Project ............................................................... 173

     Rob Houtepen ‑ Nikola Biller‑Andorno ‑ Donna Dickenson ‑ Paolo Vineis

     Reidar Lie ‑ Ruud ter Meulen

 

     Notes on the Contributors ................................................................................................. 177

     Index of Names .................................................................................................................... 179

     Index         ................................................................................................................................ 181